Opportunity Information: Apply for PAR 24 251
The Animal and Veterinary Innovation Centers (U18) funding opportunity (PAR 24-251) is a Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) initiative designed to build long-term, collaborative partnerships with academic research institutions. Through cooperative agreements, CVM is looking to establish a set of designated “Innovation Centers” that can align research capacity with FDA priority needs in animal health, veterinary product development, and regulatory science. The overall goal is to create durable, multi-year relationships where funded centers generate evidence, tools, and approaches that help move promising interventions and technologies toward practical use while also strengthening the science FDA relies on for oversight and decision-making.
A major focus area is Highly Pathogenic Avian Influenza (HPAI). The FOA emphasizes research that supports the development of interventions to prevent, control, or eliminate HPAI virus in animals, as well as interventions that reduce viral circulation in the broader ecosystem. In practical terms, this can include work that improves detection and surveillance approaches, develops countermeasures or management strategies that reduce transmission, or generates data that supports regulatory pathways for new veterinary interventions. The announcement also signals flexibility for future years, noting that the centers may pivot or expand into other emerging zoonotic disease threats or broader One Health topics as needs evolve, reflecting the reality that animal, human, and environmental health risks are often interconnected.
A second priority area is intentional genomic alterations in animals and the advancement of regulatory science to support this fast-moving field. CVM is seeking research that helps clarify, evaluate, and responsibly advance intentional genomic changes, with particular attention to applications that strengthen agricultural resilience, improve food security, and protect animal or public health. This component is not just about creating or testing new genomic approaches; it is also about producing the kinds of validation methods, risk assessment frameworks, and standards that can help regulators and developers understand performance, safety, and intended outcomes. The emphasis on “regulatory science” highlights that FDA wants research outputs that are directly useful for evaluating and guiding real-world products and innovations.
The third core area targets veterinary medical product development for unmet needs, especially where market forces often leave gaps. The FOA prioritizes research that supports products for minor species, minor uses in major species, and other unmet veterinary medical needs in major species that create a meaningful animal or public health burden. The major species explicitly referenced include dogs, cats, horses, cattle, pigs, chickens, and turkeys. This priority recognizes that many important conditions lack well-supported, appropriately studied treatments or preventives, particularly for less common species or for narrower indications where traditional commercial development may be limited. By supporting research that can de-risk development and clarify pathways, FDA aims to help enable more options for veterinarians, producers, and animal owners while addressing broader health impacts.
Structurally, this is a discretionary funding opportunity using a cooperative agreement mechanism (U18). That matters because cooperative agreements typically involve substantial federal scientific or programmatic involvement compared to standard grants, meaning applicants should be prepared for active collaboration with CVM and alignment with FDA priorities over time. The activity category is listed under Agriculture, Consumer Protection, Food and Nutrition, and the CFDA number is 93.103. The opportunity is intended for higher education institutions, including both public/state-controlled and private institutions, and the eligibility language also includes “others,” indicating potential flexibility depending on the specific application and FOA terms.
The program strongly encourages applications from a wide range of institutions, including Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). This emphasis reflects a desire to broaden participation and strengthen the national research ecosystem by supporting diverse institutional perspectives and regional capabilities, which can be particularly important in applied animal health and agricultural research.
In terms of scale and timing, the award ceiling is $1,250,000, and FDA anticipates making about 8 awards. The original closing date listed is May 12, 2028, and the opportunity was created on June 20, 2024. Overall, this FOA is best understood as an effort to stand up a network of academically anchored centers that can deliver practical, regulator-relevant research in three key domains: controlling HPAI and related One Health threats, advancing science for intentional genomic alterations in animals, and closing critical gaps in veterinary product availability for both minor and major species.Apply for PAR 24 251
- The Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Animal and Veterinary Innovation Centers (U18)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on 2024-06-20.
- Applicants must submit their applications by 2028-05-12.
- Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
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Applicants who have applied for this opportunity (PAR 24 251) also looked into and applied for these:
| Funding Opportunity |
|---|
| Single Source Cooperative Agreement to Support HPAI H5N1 Research at Cornell University (U18) - Clinical Trails Not Allowed Apply for RFA FD 24 042 Funding Number: RFA FD 24 042 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,150,000 |
| Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required Apply for RFA FD 25 001 Funding Number: RFA FD 25 001 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $650,000 |
| Laboratory Flexible Funding Model (LFFM) Apply for RFA FD 25 007 Funding Number: RFA FD 25 007 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,500,000 |
| A Research Study of Contaminants in School Meals (U18) Apply for RFA FD 25 024 Funding Number: RFA FD 25 024 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $2,000,000 |
| Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed Apply for PAR 25 003 Funding Number: PAR 25 003 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $300,000 |
| Food Safety Capacity and Infrastructure Building (U2F) Apply for RFA FD 25 019 Funding Number: RFA FD 25 019 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,000,000 |
| Conformance with the Egg Regulatory Program Standards Apply for RFA FD 25 021 Funding Number: RFA FD 25 021 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $47,000 |
| Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional) Apply for RFA FD 25 017 Funding Number: RFA FD 25 017 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $600,000 |
| NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens Apply for PAR 25 014 Funding Number: PAR 25 014 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $200,000 |
| Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required) Apply for RFA FD 25 020 Funding Number: RFA FD 25 020 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $900,000 |
| Reducing Fraud and Lowering Barriers to the Production of Drugs in Shortage by Outsourcing Facilities Apply for RFA FD 25 023 Funding Number: RFA FD 25 023 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $3,000,000 |
| FDA's Integrated Food Safety System Training Delivery and Development Apply for RFA FD 25 016 Funding Number: RFA FD 25 016 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,000,000 |
| Establishing the Integrated Food Safety System (IFSS) Regulatory and Laboratory Training System (RLTS) National Coordination Center (NCC) and Learning Management System (LMS) Apply for RFA FD 25 005 Funding Number: RFA FD 25 005 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,750,000 |
| Applied Regulatory Science Research to Evaluate Cardiotoxicity of Oncology Therapeutics (U01) Clinical Trial Optional Apply for RFA FD 25 015 Funding Number: RFA FD 25 015 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $500,000 |
| Federal and State Integration Activities to Advance Cooperation and Regulatory Standards Among Animal Food Safety Regulatory Programs Apply for RFA FD 25 022 Funding Number: RFA FD 25 022 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $600,000 |
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